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5 Facts you should know about

Hypopituitarism

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1

Hypopituitarism refers to a deficiency of one or more hormones produced by the anterior pituitary or released from the posterior pituitary

2

Onset can be acute or insidious, and the most common cause in adulthood is a pituitary adenoma or treatment with pituitary surgery, or radiotherapy

3

Most commonly, growth hormone (GH) is lost first, then gonadotropins, and finally thyroid-stimulating hormone (TSH) and adrenocorticotropic hormone (ACTH)

4

Pituitary dysfunction must be distinguished from anorexia nervosa, chronic liver disease, myotonia dystrophica, or polyglandular autoimmune disease

5

Hypopituitarism is associated with excess mortality, a key risk factor being cortisol deficiency due to adrenocorticotropic hormone deficiency

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